Thursday, 21 March 2019

Biogen halts study of Alzheimer’s drug, once pinned as “the last great hope for AD”. At this point, 4 Anti-Aβ mAbs have failed 9 big Ph3 trials, 3 γ-Secretase inhibitors showed cognitive worsening, 4 BACE inhibitors showed cognitive worsening. Global pipeline for AD looks bleak.

Biogen halts study of Alzheimer’s drug, once pinned as “the last great hope for AD”. At this point, 4 Anti-Aβ mAbs have failed 9 big Ph3 trials, 3 γ-Secretase inhibitors showed cognitive worsening, 4 BACE inhibitors showed cognitive worsening. Global pipeline for AD looks bleak. submitted by /u/SirT6
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